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The Progesterone Cliff
12 min readarticle
Nadia is standing behind the pharmacy counter on her lunch break, reading something on her phone that is about to change how she understands the last eighteen months of her life. She is reading about progesterone. Not the reproductive functions. She knows those. The neurological functions. The par...
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Get full access to this lesson and the entire Anxiety in Perimenopause — 8-Week Evidence-Based Program program with a Wellls membership.
In this lesson you will learn:
- Progesterone converts to allopregnanolone, which modulates GABA-A receptors identically to how benzodiazepines work
- Progesterone decline starts in the late 30s, often before any menstrual cycle changes
- The pregnenolone steal creates a biochemical trap: stress depletes progesterone, which increases anxiety, which increases stress
- +2 more takeaways
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