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Both/And

12 min readarticle

Evening. The kitchen is dim and the kids are somewhere upstairs and the house has that specific quality of sound where you can hear the furnace and the distant television and nothing else. Claudia stands at the counter. An omega-3 supplement bottle in front of her. 2,000 mg EPA/DHA. She bought it a...

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In this lesson you will learn:

  • SMILE trial (Blumenthal, Duke): exercise comparable to sertraline for MDD — 46% remission, 1-year follow-up showed exercise as strongest predictor of maintained remission
  • CANMAT guidelines list exercise as first-line for mild-to-moderate depression — not an add-on, first-line
  • Five women: lifestyle-only, medication-only, HRT-only, all-three, and treatment-resistant — all exist and all are valid
  • +2 more takeaways

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