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When the Floor Comes Up

12 min readarticle

Week three of the SSRI. A Thursday. Claudia notices it the way you notice the furnace has kicked on — not the heat itself, but the absence of the thing that was wrong. She is not happy. She is not even what she would call better. She is... floor. The lowest days are survivable instead of bottomless...

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Get full access to this lesson and the entire Depression in Perimenopause — 8-Week Program program with a Wellls membership.

In this lesson you will learn:

  • The SMILES trial (Jacka 2017): 32.3% remission from dietary intervention alone, NNT of 4.1 — comparable to antidepressants for mild-to-moderate depression
  • SSRI addresses serotonergic reuptake; Mediterranean diet addresses neuroinflammation, gut microbiome, tryptophan availability, and oxidative stress
  • Depression drives comfort food cravings that increase inflammation that deepens depression — the loop has a door in the kitchen
  • +1 more takeaway

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