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Your Body's Off Switch Disappeared

14 min readarticle

Grace is handing the sleep hygiene pamphlet to a patient again. The woman across the triage desk is 52, dark circles deeper than Grace's own. She is describing the same pattern: the 3 AM wakings, the racing heart, the exhaustion that somehow cannot produce sleep. Grace slides the laminated sheet ac...

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Get full access to this lesson and the entire Perimenopause Insomnia — 8-Week Program program with a Wellls membership.

In this lesson you will learn:

  • Progesterone decline eliminates your body's endogenous sedative (allopregnanolone) that acts on the same receptors as Ambien
  • Estrogen fluctuation narrows the thermoneutral zone via KNDy neurons, triggering night sweats from tiny temperature shifts
  • The cortisol awakening response shifts to 3-4 AM, creating a self-reinforcing loop of sleep loss and HPA axis dysregulation
  • +1 more takeaway

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